Coeliac disease in Primary Care. A diagnosis to take into account
Reference of this article: Valverde Gómez F, Camps Rubiol T, Kirchschläger E, Roldán Martín MB, Hernández Lorca MA, Mendienta Sanz E. Coeliac disease in Primary Care. A diagnosis to take into account. Rev Pediatr Aten Primaria. 1999;1:253-264.
Published in Internet: 30-06-1999 - Visits: 8506
Celiac disease is defined as a condition of the proximal small bowel that is associated
with a permanent intolerance to gluten, a protein contained in some cereals. The pathogenesis
of the disease probably relies on the interaction of genetic and immunologial factors celiac disease relies on the interaction of genetic and immunological factors. The prevalence
of celiac disease is not well-kwon. Clinical features may be very variable and the classic
mode of presentation (related to malabsorption) coexists with other monosymptomatic or
even asymptomatic forms of the disease. New diagnostic tools (antigliadin, antiendomysium
and antireticulin antibodies) are used for screening celiac disease. The diagnosis is based
on histological findings (jejunal biopsy). Removal of gluten from the diet is obligatory
because celiac disease may be associated with long-term complications, especially with intestinal
Objetives: To evaluate the prevalence and the clinical features of the coeliac disease at
a Primary Healthcare level.
Methods: Retrospective study of the pediatric population attended in five health centres.
Results: Twenty-two of 6.578 children had celiac disease (prevalence:1/295). The most
frequent clinical presentation of the disease was the malabsortive form. Celiac disease was
associated with other immunological processes (dematitis herpetiformis, type 1 diabetes
mellitus, IgA deficiency) in some patients. Antigliadin and antiendomysium antibodies were
sensitive tests in screening for celiac disease.
Keywords● Celiac disease ● Prevalence ● Primary care