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Vol. 17 - Num. 67

Childhood and Adolescence PrevInfad/PAPPS Group

What is the appropriate age for the introduction of gluten in the diet of infants?

José Galbe Sánchez-Venturaa, Jaime García Aguadob, Ana Martínez Rubioc, José M.ª Mengual Gild, Manuel Merino Moínae, Carmen Rosa Pallás Alonsof, Francisco Javier Sánchez Ruiz-Cabellog, Julia Colomer Revueltah, Olga Cortés Ricoi, M.ª Jesús Esparza Olcinab, Javier Soriano Fauraj, Grupo PrevInfad/PAPPS Infancia y Adolescenciak

aPediatra. CS Torrero La Paz. Zaragoza. España.
bPediatra. Madrid. España.
cPediatra. CS de Camas. Sevilla. España.
dPediatra. CS Delicias Sur. Zaragoza. España.
ePediatra. CS El Greco. Getafe. Madrid. España.
fServicio de Neonatología. Hospital Universitario 12 de Octubre. Madrid. España.
gPediatra. CS Zaidín Sur. Granada. España.
hDepartamento de Pediatría, Obstetricia y Ginecología. Unidad de Pediatría. Universidad de Valencia. Valencia. España.
iPediatra. CS Canillejas. Madrid. España.
jPediatra. CS Fuensanta. Valencia. España.
kJosé María Mengual Gil (coord.).

Correspondence: J Galbe. E-mail:

Reference of this article: Galbe Sánchez-Ventura J, García Aguado J, Martínez Rubio A, Mengual Gil JM, Merino Moína M, Pallás Alonso CR, et al. What is the appropriate age for the introduction of gluten in the diet of infants? Rev Pediatr Aten Primaria. 2015;17:271-74.

Published in Internet: 04-09-2015 - Visits: 16151


A well designed clinical trial, with low risk of bias, published in 2014, shows that, in celiac disease high risk infants, small amounts of gluten in the diet don’t reduce the incidence of celiac disease at three years of age; moreover, breastfeeding didn’t have any effect in the disease incidence at three years of age either. These results are clearly contradictory with the 2008 ESPGHAN recommendations. The conclusion is the adherence to the recommendation of exclusive breastfeeding the first six months of life and that the progressive introduction of gluten between 4 and 6 months of age do not reduce celiac disease incidence.


Celiac disease Gluten



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