Vol. 22 - Num. 86
aMIR-Pediatría. Hospital Universitario Miguel Servet. Zaragoza. España.
bServicio de Pediatría. Hospital Universitario Miguel Servet. Zaragoza. España.
cServicio de Reumatología. Hospital Universitario Miguel Servet. Zaragoza. España.
Correspondence: M Marín. E-mail: email@example.com
Reference of this article: Marín Andrés M, Miralbés Terraza S, Medrano San Ildefonso M. Isolated thrombopenia is not always primary immune thrombopenia. Rev Pediatr Aten Primaria. 2020;22:e61-e64.
Published in Internet: 04-06-2020 - Visits: 1340
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology that affects multiple organs and systems. Pediatric SLE is more frequent in girls and has a peak incidence between 12-16 years. The most frequent clinical manifestations are constitutional symptoms, arthritis, malar erythema and hematological abnormalities. Thrombopenia appears in 50% of cases and is the initial manifestation in 15% of cases of SLE of pediatric onset, although it may take several years before the appearance of other manifestations of SLE. Between 20 and 30% of children with primary immune thrombopenia and serum positive ANA will subsequently develop SLE.
Keywords● Primary immune thrombopenia ● Systemic lupus eythematosus ● Thrombocytopenia
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