Vol. 24 - Num. 94
Clinical Reviews in Digestive Diseases
Severe diarrhoea in a previously healthy infant: a diagnostic challenge
Sandra Pérez Salasa, Marta García Vegaa, Sandra García Barbab, Nerea Salmón Rodríguezc, Luis Ignacio González Granadosc, Enrique Salcedo Lobatoa, Enrique Medina Beníteza
aSección de Gastroenterología, Hepatología y Nutrición Pediátrica. Servicio de Pediatría. Hospital Universitario 12 de Octubre. Madrid. España.
bServicio de Pediatría. Hospital Universitario de Fuenlabrada. Fuenlabrada. Madrid. España.
cUnidad de Inmunodeficiencias. Servicio de Pediatría. Hospital Universitario 12 de Octubre. Madrid. España.
Correspondence: S Pérez. E-mail: sandrapsra@gmail.com
Reference of this article: Pérez Salas S, García Vega M, García Barba S, Salmón Rodríguez N, González Granados LI, Salcedo Lobato E, et al. Severe diarrhoea in a previously healthy infant: a diagnostic challenge. Rev Pediatr Aten Primaria. 2022;24 [en prensa].
Published in Internet: 02-06-2022 - Visits: 8560
Abstract
Although the most frequent cause of childhood diarrheal processes is infection, in the case of severe and prolonged symptoms in infants, congenital causes such as genetic disorders or immunodeficiencies must be ruled out. Cytomegalovirus (CMV) colitis is a rare cause of chronic diarrhoea in immunocompetent children. In general, it is a mild and self-limiting disease, so the possibility of immunodeficiency should be considered in cases with a more severe course. Performance of an endoscopic examination is recommended in these patients, and antiviral treatment is required in those with more severe forms of disease or with confirmed immunosuppression.
Keywords
● Chronic diarrhea ● Cytomegalovirus
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