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Vol. 21 - Num. 84

Clinical Reviews

Acquired factor XI deficiency. A case report

Marina Ortiz Palaciosa, Carlos Iglesias Gómezb, Begoña Pelegrín Lópezc, M.ª Ángeles Castellar Reched

aServicio de Pediatría. Hospital Clínico Universitario Virgen de la Arrixaca. Murcia. España.
bPediatra. CS Alcantarilla-Sangonera. Murcia. España.
cPediatra. CS Alcantarilla-Sangonera. Alcantarilla. Murcia. España.
dPediatra. CS Alcantarilla-Casco. Alcantarilla. Murcia. España.

Correspondence: C Iglesias. E-mail:

Reference of this article: Ortiz Palacios M, Iglesias Gómez C, Pelegrín López B, Castellar Reche MA. Acquired factor XI deficiency. A case report. Rev Pediatr Aten Primaria. 2019;21:e205-e207.

Published in Internet: 10-10-2019 - Visits: 9059


Factor XI deficiency is a hereditary coagulation disorder with a quantitative and/or qualitative reduction of factor XI due to F11 gene mutations. This is a common entity in Ashkenazi community, which can be underestimated in Caucasians. It can debut at any age with variable and unpredictable symptoms, showing poor relation between factor XI activity levels and bleeding symptoms. It can be diagnosed after a basic coagulation exam (lengthening activated partial thromboplastin time [APTT]) and factor XI levels measure. We present a factor XI deficiency clinical case for spreading this entity to the pediatric community.


Factor XI deficiency Haemophilia Vaginal bleeding



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