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Vol. 24 - Num. 95

Original Papers

Sensitivity of the Panbio COVID-19 Antigen-Detecting Rapid Diagnostic Test in Primary Care

Ana M.ª Alonso Rubioa, Mercedes Garrido Redondob, M.ª Rosario Bachiller Luquec, M.ª Luisa Vega Gutiérrezc, Cristina García de Riverad, Beatriz Liras Muñoze, Teresa Palencia Ercillae, Mónica Sanz Fernándezf, María Alonso Ballesterosg, Mari Fe Muñoz Morenoh, Paula Borregón Garridoi

aPediatra. CS Covaresa-Parque Alameda. Valladolid. España
bPediatra. CS La Tórtola. Valladolid. España.
cPediatra. CS Pilarica. Valladolid. España.
dPediatra. CS Rondilla. Valladolid. España.
ePediatra. CS Cuéllar. Cuéllar. Segovia. España.
fPediatra. CS Pisuerga. Arroyo de la Encomienda. Valladolid. España.
gPediatra. CS Medina del Campo. Valladolid. España.
hPediatra. Unidad de Apoyo a la Investigación. Hospital Clínico Universitario. Valladolid. España.
iEstudiante de Medicina. Facultad de Medicina. Universidad de Valladolid. Valladollid. España.

Correspondence: AM Alonso . E-mail: alonsoam04@hotmail.com

Reference of this article: Alonso Rubio AM, Garrido Redondo M, Bachiller Luque MR, Vega Gutiérrez ML, García de Rivera C, Liras Muñoz B, et al. Sensitivity of the Panbio COVID-19 Antigen-Detecting Rapid Diagnostic Test in Primary Care. Rev Pediatr Aten Primaria. 2022;24:e283-e289.

Published in Internet: 21-09-2022 - Visits: 922

Abstract

Introduction and objectives: primary care pediatricians need reliable Rapid Diagnostic Techniques (RDT) to prevent the spread of COVID 19 disease through early and effective screening, while awaiting a vaccine. The objective of this work was to evaluate as a novelty in Primary Care in both adults and children, symptomatic and asymptomatic contacts, the sensitivity (S) of the Abbott laboratory SARS-CoV-2Panbio antigen test with respect to the polymerase chain reaction (PCR).

Patients and methods: a total of 591 patients (222 under 14 years of age) from 7 Primary Care health centers (249 symptomatic and 342 contacts) were included. S and specificity (E) were calculated along with their 95% confidence intervals. The independence of the two results has been analyzed using the Mc Nemar test.

Results: the S of the test in adults was 81% (95% CI: 66.16-96.34) and in children 80% (95% CI: 34.94-100) within the first 5 days. While in contacts the S was evaluated in the first 5 days in adults [68% (CI 95%: 51.13- 86.37)], from 5 to 9 days (85%) and children [66% (CI 95%: 30.31-100)]. Household contact was the most frequent type of contact, in 52% of the cases. E was 100% in all cases

Conclusions: the Panbio SARS-CoV-2rapid antigen test can be useful for diagnosing adults and children the first five days of onset of symptoms, and from 5th to 9th day in contacts of people with COVID 19 confirmed. We need further studies that provide wider explanation for this last result.

Keywords

COVID-19 Point-of-care diagnostics Primary Care SARS-CoV-2

 

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