Vol. 28 - Num. 111

Evidence based Pediatrics

Gender affirming hormone therapy: what evidence do we have so far?

Ana Gámez Belmontea, M.ª José Rivero Martínb

aServicio de Pediatría. Hospital de Antequera. Málaga. España
bServicio de Pediatría. Hospital de Fuenlabrada. Madrid. España.

Correspondence: A Gámez. E-mail: ana_gamez_@hotmail.com

Reference of this article: Gámez Belmonte A, Rivero Martín MJ. Gender affirming hormone therapy: what evidence do we have so far? . Rev Pediatr Aten Primaria. 2026;28:391-3. https://doi.org/10.60147/bea99816

Published in Internet: 29-09-2026 - Visits: 92

Abstract

Authors’ conclusions: there is a great uncertainty around the gender affirming hormone therapy and further studies with rigorous methodology are needed.

Reviewers’ commentary: gender affirmation therapy cannot be accepted or rejected with the results this systematic review provides, since the evidence of the included studies is low or very low.

Keywords

● Gender and Health ● Gender dysphoria ● Gender identity