Authors' conclusions: Umbilical cord blood transfusion is safe and provides benefits for improving gross motor function in some children with cerebral palsy, especially younger children with milder cerebral palsy.

Reviewers' comment: While promising, umbilical cord blood transfusion in childhood cerebral palsy is of questionable long-term safety and offers only uncertain gross motor function benefits to certain children (under 5 years of age with mild cerebral palsy) and at high doses of total nucleated cells. At present, in our opinion, a general recommendation cannot be made.