Vol. 28 - Num. 111
Evidence based Pediatrics
Gender-affirming hormone therapy: what is the evidence so far?
Ana Gámez Belmontea, M.ª José Rivero Martínb
aServicio de Pediatría. Hospital de Antequera. Málaga. España
bServicio de Pediatría. Hospital de Fuenlabrada. Madrid. España.
Correspondence: A Gámez. E-mail: ana_gamez_@hotmail.com
Reference of this article: Gámez Belmonte A, Rivero Martín MJ. Gender-affirming hormone therapy: what is the evidence so far? . Rev Pediatr Aten Primaria. 2026;28:391-3. https://doi.org/10.60147/bea99816
Published in Internet: 29-09-2026 - Visits: 505
Abstract
Authors’ conclusions: there is considerable uncertainty regarding gender-affirming hormone therapy, and further studies with rigorous methodology are needed.
Reviewers’ commentary: gender-affirming therapy cannot be accepted or rejected with the findings of this systematic review, as the quality of the evidence of the included studies is low or very low.
Keywords
● Gender and health ● Gender dysphoria ● Gender identity