Vol. 27 - Num. 107

Clinical Reviews

What if ADH-ditionally there’s Mycoplasma pneumoniae?

Sara Gracia Baldovína, Violeta Fuertes Oreraa, Claudia Montón Jiméneza, Margarita Martínez Martínezb, Mercedes Cemeli Canob

aMIR-Pediatría. Hospital Universitario Materno Infantil Miguel Servet. Zaragoza. España.
bPediatra. CS Fuentes Norte. Zaragoza. España.

Correspondence: S Gracia. E-mail: sarigraciab@gmail.com

Reference of this article: Gracia Baldovín S, Fuertes Orera V, Montón Jiménez C, Martínez Martínez M, Cemeli Cano M. What if ADH-ditionally there’s Mycoplasma pneumoniae? . Rev Pediatr Aten Primaria. 2025;27:277-81. https://doi.org/10.60147/1357bcf2

Published in Internet: 26-08-2025 - Visits: 2245

Abstract

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is characterized by an abnormal increase in the secretion of ADH in absence of the appropriate physiological stimuli, leading to dilutional hyponatremia, decreased serum osmolality and increased urinary osmolality and sodium excretion.

We describe the case of a 12-year-old girl who developed incomplete SIADH during her stay in the intensive care unit (ICU) in the context of community-acquired pneumonia with a positive PCR for M. pneumoniae.

SIADH is a common cause of transient hyponatremia in children with respiratory infections. It has been associated with more severe disease, prolonged hospital stays and a higher likelihood of ICU admission, making it essential to consider electrolyte imbalances in the management of these patients.

Keywords

Mycoplasma pneumoniae Hyponatremia Inappropriate ADH syndrome Pneumonia