AZ Pediatría
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Vol. 25 - Num. 100

Clinical Reviews

Iron deficiency and Restless Legs Syndrome

Silvia de las Nieves Ortega Péreza, M.ª Amparo Sangil Gonzáleza, Domingo Cañizo Fernándeza, Patricia Isabel Pérez González a

aPediatras. CS Arucas. Arucas. Área Norte de Gran Canaria. Servicio Canario de Salud. Las Palmas. Islas Canarias. España.

Correspondence: SN Ortega. E-mail:

Reference of this article: Ortega Pérez SN, Sangil González MA, Cañizo Fernández D, Pérez González PI. Iron deficiency and Restless Legs Syndrome . Rev Pediatr Aten Primaria. 2023;25:415-20.

Published in Internet: 19-12-2023 - Visits: 4217


Restless Legs Syndrome is a sensory-motor neurological disorder that is underdiagnosed in childhood.

The etiology is unclear, but genetic factors, dopaminergic dysfunction and low iron stores play an important role.

The presentation in children is very unspecific and diagnosis can sometimes be difficult, it is important to get an early diagnose of this pathology because of its impact on the patient´s quality of life.

We present the case of a 4 year old girl who consults for symptoms compatible with Restless Legs Syndrome associated with iron deficiency, who showed significant improvement after iron treatment until the symptoms disappeared completely.


Childhood Iron deficiency Restless Legs Syndrome Willis-Ekbom disease


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