Genital mass in a neonate; diagnostic orientation

Skene’s paraurethral cyst is a benign cystic tumor dependent on the Skene glands and adjacent to the urethral meatus, which can drain whitish mucoid content to the vaginal introitus. The physical examination determines the diagnosis, leaving the ultrasound study for those doubtful cases and that presented with urinary obstruction. Management should be conservative and a correct diagnostic approach is essential to rule out other processes that would require surgical treatment such as imperforate hymen, urethral prolapse, ureterocele prolapse, etc. The case of a full-term newborn in whom an interlabial genital mass was discovered in her first 24 hours of life.