Vol. 18 - Num. 70
Critical appraisal in small doses
aServicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
Correspondence: M Molina. E-mail: firstname.lastname@example.org
Reference of this article: Molina Arias M. Re-randomization: in search of the simple size. Rev Pediatr Aten Primaria. 2016;70:185-8.
Published in Internet: 13-06-2016 - Visits: 6361
There are some situations or conditions in which patients require treatment on multiple occasions. The most common in clinical trials is to randomize patients once in each trial. However, the sample can be increased if recruitment allows each patient to be randomized each time requiring treatment and not only once at the beginning of the trial. This is the procedure known as re-aleatorización.
Keywords● Clinical Trials ● Re-randomization ● Sample size
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