Advertisement
Cine y Pediatría 8
Article not rated

Vol. 14 - Num. 53

Brief Reports

Hyperandrogenism: precocious pubarche and polycystic ovary syndrome. Etiology and therapeutic possibilities

Lorena García Blancoa, C Azcona San Juliánb

aPediatra. CS de Ansoáin. Servicio Navarro de Salud-Osasunbidea. Pamplona. Navarra. España.
bServicio de Pediatría, Unidad de Endocrinología Pediátrica. Clínica Universidad de Navarra. Pamplona. España.

Correspondence: L García. E-mail: lgblanco@unav.es

Reference of this article: García Blanco L, Azcona San Julián C. Hyperandrogenism: precocious pubarche and polycystic ovary syndrome. Etiology and therapeutic possibilities. Rev Pediatr Aten Primaria. 2012;14:61-7.

Published in Internet: 13-04-2012

Abstract

The synthesis of androgens in women is produced in the adrenal gland, ovary, and peripheral target tissues for androgen action (skin, muscle and adipose tissue).

Excessive androgen production (or hyperandrogenism) in childhood and adolescence may determine alterations in these target tissues, determining the onset of hirsutism, acne, menstrual disorders or virilization, whose intensity and time of onset depend on the origin of the excess production of androgens.

The etiology of hyperandrogenism will vary according to age. Therefore, in the prepubertal period in the absence of androgen overproduction gonadal maturation have originated in the adrenal gland in most cases, while in the peripubertal post-pubertal period the ovary is the main cause.

Keywords

Hyperandrogenism Policystic ovary Pubarche

 

Comments

This article has no comments yet.