Prevention of child psychomotor impairment due to iodine deficiency
Reference of this article: Galbe Sánchez-Ventura J, Grupo PrevInfad/PAPPS Infancia y Adolescencia. Prevention of child psychomotor impairment due to iodine deficiency. Rev Pediatr Aten Primaria. 2007;9:51-70.
Published in Internet: 31-03-2007
Iodine is one of the main elements for human development; it intervenes in the synthesis
of thyroid hormones and neurodevelopment. Iodine deficiency affects to one third
of world population. Iodine deficiency is responsible of disorders as goitre and infant cretinism,
and it raises child mortality. Mild iodine deficiency can also be responsible of
mild neurologic developmental disorders as borderline cognitive skills or attention deficit
and hyperactivity disorders. In Spain there are communities with mild iodine deficiency.
One of the methods to evaluate the community iodine deficit is to know de ratio of the
neonatal TSH < 5 MU/l from neonatal mass screening. During pregnancy yoduria often
decreases under level of deficiency (defined by OMS). Nowadays there aren?t proofs of
efficacy of iodine supplementation since the beginning of pregnancy in the long term
neurodevelopment of the child. Authors recommend iodized salt use for all the population
and to know the value of TSH neonatal screening of each child. It is necessary to
study the effects of iodine supplementation during pregnancy in the long term neurodevelopment
of the children.
Keywords● Infant ● Infant, newborn ● Iodine ● Nervous system disorders ● Neurological manifestations ● Pregnancy ● Screening ● Thyrotropin