Advertisement
Cuentos para crecer por dentro

   
Share |
 Article not rated yet 

Critical appraisal in small doses

Sequential designs: early interruption of clinical trial

Authors:

Molina Arias Ma

aServicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España. Grupo de Trabajo de Pediatría Basada en la Evidencia AEP/AEPap. Editor de www.cienciasinseso.com.

Correspondence: M Molina. Email: mma1961@gmail.com

Reference of this article.:

Molina Arias M. Diseños secuenciales: interrupción precoz del ensayo clínico. Rev Pediatr Aten Primaria. 2017;19:87-90.

Published in Internet: 04/01/2017

Abstract:

Unlike in the usual parallel clinical trials, in sequential designs the sample size is not fixed, but depends on the results of interim analysis that will be carried out throughout the study. The results of these interim analyzes will determine if the trial can be interrupted or must continue until reaching a previously set maximum sample size.

Keywords: Interim analysis. Sequential trials.


 


Comments

This article has no comments yet.

ISSN 2174-4106  Publicación Open Acess, incluida en DOAJ, sin cargo por publicación.

Privacy Policy | Web map | Copyright 2017 Lúa Ediciones 3.0 | Contact